abstract：:The Lyme disease spirochete Borrelia burgdorferi is unique among bacteria in its large number of lipoproteins that are encoded by a small, exceptionally fragmented, and predominantly linear genome. Peripherally anchored in either the inner or outer membrane and facing either the periplasm or the external environment, ...

journal_title：Journal of bacteriology

authors： Dowdell AS,Murphy MD,Azodi C,Swanson SK,Florens L,Chen S,Zückert WR

更新日期：2017-02-28 00:00:00

abstract：:Anabaena variabilis ATCC 29413 has one Mo nitrogenase that is made under oxic growth conditions in specialized cells called heterocysts and a second Mo nitrogenase that is made only under anoxic conditions in vegetative cells. The two large nif gene clusters responsible for these two nitrogenases are under the control...

journal_title：Journal of bacteriology

authors： Vernon SA,Pratte BS,Thiel T

更新日期：2017-01-30 00:00:00

abstract：:As adhesion fimbriae are a major virulence factor for many pathogenic Gram-negative bacteria, they are also potential targets for antibodies. Fimbriae are commonly required for initiating the colonization that leads to disease, and their success as adhesion organelles lies in their ability to both initiate and sustain...

journal_title：Journal of bacteriology

authors： Singh B,Mortezaei N,Savarino SJ,Uhlin BE,Bullitt E,Andersson M

更新日期：2016-12-13 00:00:00

abstract：:Most bacteria are likely to face osmotic challenges, but there is yet much to learn about how such environmental changes affect the architecture of bacterial cells. Here, we report a cell-biological study in model organisms of the genus Streptomyces, which are actinobacteria that grow in a highly polarized fashion to ...

journal_title：Journal of bacteriology

authors： Fuchino K,Flärdh K,Dyson P,Ausmees N

更新日期：2016-12-13 00:00:00

abstract：:Horizontal acquisition of novel chromosomal genes is considered to be a key process in the evolution of bacterial pathogens. However, the identification of gene presence or absence could be hindered by the inconsistencies in bacterial genome annotations. Here, we performed a cross-annotation of omnipresent core and mo...

journal_title：Journal of bacteriology

authors： Paul S,Sokurenko EV,Chattopadhyay S

更新日期：2016-11-04 00:00:00

abstract：:Neisseria gonorrhoeae (gonococci) and Neisseria meningitidis (meningococci) are human pathogens that cause gonorrhea and meningococcal meningitis, respectively. Both N. gonorrhoeae and N. meningitidis release a number of small peptidoglycan (PG) fragments, including proinflammatory PG monomers, although N. meningitidi...

journal_title：Journal of bacteriology

authors： Chan JM,Dillard JP

更新日期：2016-10-07 00:00:00

abstract：UNLABELLED:The Mycobacterium tuberculosis exported repetitive protein (RvErp) is a crucial virulence-associated factor as determined by its role in the survival and multiplication of mycobacteria in cultured macrophages and in vivo Although attempts have been made to understand the function of Erp protein, its exact ro...

journal_title：Journal of bacteriology

authors： Ganaie AA,Trivedi G,Kaur A,Jha SS,Anand S,Rana V,Singh A,Kumar S,Sharma C

更新日期：2016-09-22 00:00:00

abstract：:Bacillus subtilis possesses different enzymes for the utilization of plant cell wall polysaccharides. This includes a gene cluster containing galactan degradation genes (ganA and ganB), two transporter component genes (ganQ and ganP), and the sugar-binding lipoprotein-encoding gene ganS (previously known as cycB). The...

journal_title：Journal of bacteriology

authors： Watzlawick H,Morabbi Heravi K,Altenbuchner J

更新日期：2016-09-22 00:00:00

abstract：UNLABELLED:Helicobacter pylori must be able to rapidly respond to fluctuating conditions within the stomach. Despite this need for constant adaptation, H. pylori encodes few regulatory proteins. Of the identified regulators, the ferric uptake regulator (Fur), the nickel response regulator (NikR), and the two-component ...

journal_title：Journal of bacteriology

authors： Servetas SL,Carpenter BM,Haley KP,Gilbreath JJ,Gaddy JA,Merrell DS

更新日期：2016-08-25 00:00:00

abstract：UNLABELLED:The latent period of phage T4, normally ∼25 min, can be extended indefinitely if the infected cell is superinfected after 5 min. This phenomenon, designated lysis inhibition (LIN), was first described in the 1940s and is genetically defined by mutations in diverse T4 r genes. RI, the main effector of LIN, ha...

journal_title：Journal of bacteriology

authors： Chen Y,Young R

更新日期：2016-08-25 00:00:00

abstract：UNLABELLED:Streptococcus pneumoniae is able to integrate exogenous DNA into its genome by natural genetic transformation. Transient accumulation of high levels of the only S. pneumoniae alternative σ factor is insufficient for development of full competence without expression of a second competence-specific protein, Co...

journal_title：Journal of bacteriology

authors： Tovpeko Y,Bai J,Morrison DA

更新日期：2016-08-11 00:00:00

abstract：UNLABELLED:The σE envelope stress response is an essential signal transduction pathway which detects and removes mistargeted outer membrane (OM) β-barrel proteins (OMPs) in the periplasm of Escherichia coli It relies on σE, an alternative sigma factor encoded by the rpoE gene. Here we report a novel mutation, a nucleot...

journal_title：Journal of bacteriology

authors： Konovalova A,Schwalm JA,Silhavy TJ

更新日期：2016-08-11 00:00:00

abstract：:Microbial communities span many orders of magnitude, ranging in scale from hundreds of cells on a single particle of soil to billions of cells within the lumen of the gastrointestinal tract. Bacterial cells in all habitats are members of densely populated local environments that facilitate competition between neighbor...

journal_title：Journal of bacteriology

authors： Stubbendieck RM,Straight PD

更新日期：2016-07-28 00:00:00

abstract：UNLABELLED:Corynebacterium glutamicum metabolizes sialic acid (Neu5Ac) to fructose-6-phosphate (fructose-6P) via the consecutive activity of the sialic acid importer SiaEFGI, N-acetylneuraminic acid lyase (NanA), N-acetylmannosamine kinase (NanK), N-acetylmannosamine-6P epimerase (NanE), N-acetylglucosamine-6P deacetyl...

journal_title：Journal of bacteriology

authors： Uhde A,Brühl N,Goldbeck O,Matano C,Gurow O,Rückert C,Marin K,Wendisch VF,Krämer R,Seibold GM

更新日期：2016-07-28 00:00:00

abstract：UNLABELLED:FimV is a Pseudomonas aeruginosa inner membrane protein that regulates intracellular cyclic AMP (cAMP) levels-and thus type IV pilus (T4P)-mediated twitching motility and type II secretion (T2S)-by activating the adenylate cyclase CyaB. Its cytoplasmic domain contains three predicted tetratricopeptide repeat...

journal_title：Journal of bacteriology

authors： Buensuceso RN,Nguyen Y,Zhang K,Daniel-Ivad M,Sugiman-Marangos SN,Fleetwood AD,Zhulin IB,Junop MS,Howell PL,Burrows LL

更新日期：2016-07-28 00:00:00

abstract：UNLABELLED:Many bacteria utilize actin-like proteins to direct peptidoglycan (PG) synthesis. MreB and MreB-like proteins are thought to act as scaffolds, guiding the localization and activity of key PG-synthesizing proteins during cell elongation. Despite their critical role in viability and cell shape maintenance, ver...

journal_title：Journal of bacteriology

authors： Duan Y,Sperber AM,Herman JK

更新日期：2016-07-13 00:00:00

abstract：UNLABELLED:Multiple essential small GTPases are involved in the assembly of the ribosome or in the control of its activity. Among them, ObgE (CgtA) has been shown recently to act as a ribosome antiassociation factor that binds to ppGpp, a regulator whose best-known target is RNA polymerase. The present study was aimed ...

journal_title：Journal of bacteriology

authors： Maouche R,Burgos HL,My L,Viala JP,Gourse RL,Bouveret E

更新日期：2016-06-13 00:00:00

abstract：UNLABELLED:The gene encoding a nonoxidative decarboxylase capable of catalyzing the transformation of 2-hydroxy-1-naphthoic acid (2H1NA) to 2-naphthol was identified, recombinantly expressed, and purified to homogeneity. The putative gene sequence of the decarboxylase (hndA) encodes a 316-amino-acid protein (HndA) with...

journal_title：Journal of bacteriology

authors： Pal Chowdhury P,Basu S,Dutta A,Dutta TK

更新日期：2016-05-27 00:00:00

abstract：UNLABELLED:Our laboratory recently discovered that Escherichia coli cells starved for the DNA precursor dGTP are killed efficiently (dGTP starvation) in a manner similar to that described for thymineless death (TLD). Conditions for specific dGTP starvation can be achieved by depriving an E. coli optA1 gpt strain of the...

journal_title：Journal of bacteriology

authors： Itsko M,Schaaper RM

更新日期：2016-05-13 00:00:00

abstract：UNLABELLED:Bacterial cell division is an essential and highly coordinated process. It requires the polymerization of the tubulin homologue FtsZ to form a dynamic ring (Z-ring) at midcell. Z-ring formation relies on a group of FtsZ-associated proteins (Zap) for stability throughout the process of division. In Escherichi...

journal_title：Journal of bacteriology

authors： Roach EJ,Wroblewski C,Seidel L,Berezuk AM,Brewer D,Kimber MS,Khursigara CM

更新日期：2016-05-13 00:00:00

abstract：UNLABELLED:Edwardsiella tarda is an important pathogenic bacterium that can replicate in macrophages. However, how the intramacrophage infection process affects the virulence of this bacterium is essentially unknown. Here, we show that E. tarda replicates and induces a caspase-1-dependent cell pyroptosis in a murine ma...

journal_title：Journal of bacteriology

authors： Zhang L,Ni C,Xu W,Dai T,Yang D,Wang Q,Zhang Y,Liu Q

更新日期：2016-04-28 00:00:00

abstract：UNLABELLED:It is well established that the RpoN-RpoS sigma factor (σ(54)-σ(S)) cascade plays an essential role in differential gene expression during the enzootic cycle of Borrelia burgdorferi, the causative agent of Lyme disease. The RpoN-RpoS pathway is activated by the response regulator/σ(54)-dependent activator (a...

journal_title：Journal of bacteriology

authors： Yin Y,Yang Y,Xiang X,Wang Q,Yang ZN,Blevins J,Lou Y,Yang XF

更新日期：2016-04-28 00:00:00

abstract：UNLABELLED:The Pseudomonas aeruginosa cyclic AMP (cAMP)-Vfr system (CVS) is a global regulator of virulence gene expression. Regulatory targets include type IV pili, secreted proteases, and the type III secretion system (T3SS). The mechanism by which CVS regulates T3SS gene expression remains undefined. Single-cell exp...

journal_title：Journal of bacteriology

authors： Marsden AE,Intile PJ,Schulmeyer KH,Simmons-Patterson ER,Urbanowski ML,Wolfgang MC,Yahr TL

更新日期：2016-04-14 00:00:00

abstract：UNLABELLED:Bacteriophytochrome photoreceptors (BphPs) and their cognate response regulators make up two-component signal transduction systems which direct bacteria to mount phenotypic responses to changes in environmental light quality. Most of these systems utilize single-domain response regulators to transduce signal...

journal_title：Journal of bacteriology

authors： Baker AW,Satyshur KA,Moreno Morales N,Forest KT

更新日期：2016-03-31 00:00:00

abstract：UNLABELLED:To stabilize cellular integrity in the face of environmental perturbations, most bacteria, including cyanobacteria, synthesize and maintain a strong, flexible, three-dimensional peptidoglycan lattice. Anabaena sp. strain PCC 7120 is a filamentous cyanobacterium capable of differentiating morphologically dist...

journal_title：Journal of bacteriology

authors： Videau P,Rivers OS,Ushijima B,Oshiro RT,Kim MJ,Philmus B,Cozy LM

更新日期：2016-03-31 00:00:00

abstract：UNLABELLED:Escherichia coli RtcB is a founding member of a family of manganese-dependent RNA repair enzymes that join RNA 2′,3′-cyclic phosphate (RNA>p) or RNA 3′-phosphate (RNAp) ends to 5′-OH RNA (HORNA) ends in a multistep pathway whereby RtcB (i) hydrolyzes RNA>p to RNAp, (ii) transfers GMP from GTP to RNAp to form...

journal_title：Journal of bacteriology

authors： Maughan WP,Shuman S

更新日期：2016-03-31 00:00:00

abstract：UNLABELLED:Succinic semialdehyde (SSA), an important metabolite of γ-aminobutyric acid (GABA), is a ligand of the repressor AttJ regulating the expression of the attJ-attKLM gene cluster in the plant pathogen Agrobacterium tumefaciens. While the response of A. tumefaciens to GABA and the function of attKLM have been ex...

journal_title：Journal of bacteriology

authors： Wang C,Tang D,Gao YG,Zhang LH

更新日期：2016-01-11 00:00:00

abstract：:The cyclic dinucleotides cyclic 3′,5′-diguanylate (c-di-GMP) and cyclic 3′,5′-diadenylate (c-di-AMP) have emerged as key components of bacterial signal transduction networks. These closely related second messengers follow the classical general principles of nucleotide signaling by integrating diverse signals into regu...

journal_title：Journal of bacteriology

authors： Tschowri N

更新日期：2016-01-01 00:00:00

abstract：UNLABELLED:Rhodopseudomonas palustris is an alphaproteobacterium that has served as a model organism for studies of photophosphorylation, regulation of nitrogen fixation, production of hydrogen as a biofuel, and anaerobic degradation of aromatic compounds. This bacterium is able to transition between anaerobic photoaut...

journal_title：Journal of bacteriology

authors： Pechter KB,Gallagher L,Pyles H,Manoil CS,Harwood CS

更新日期：2015-12-28 00:00:00

abstract：UNLABELLED:Neisseria meningitidis, an exclusively human pathogen and the leading cause of bacterial meningitis, must adapt to different host niches during human infection. N. meningitidis can utilize a restricted range of carbon sources, including lactate, glucose, and pyruvate, whose concentrations vary in host niches...

journal_title：Journal of bacteriology

authors： Antunes A,Golfieri G,Ferlicca F,Giuliani MM,Scarlato V,Delany I

更新日期：2015-12-07 00:00:00

abstract：UNLABELLED:Mycobacterium tuberculosis possesses a thick and highly hydrophobic cell wall principally composed of a mycolyl-arabinogalactan-peptidoglycan complex, which is critical for survival and virulence. DprE1 is a well-characterized component of decaprenyl-phospho-ribose epimerase, which produces decaprenyl-phosph...

journal_title：Journal of bacteriology

authors： Kolly GS,Mukherjee R,Kilacsková E,Abriata LA,Raccaud M,Blaško J,Sala C,Dal Peraro M,Mikušová K,Cole ST

更新日期：2015-12-01 00:00:00

abstract：UNLABELLED:TcpP and ToxR coordinately regulate transcription of toxT, the master regulator of numerous virulence factors in Vibrio cholerae. TcpP and ToxR are membrane-localized transcription factors, each with a periplasmic domain containing two cysteines. In ToxR, these cysteines form an intramolecular disulfide bond...

journal_title：Journal of bacteriology

authors： Morgan SJ,French EL,Thomson JJ,Seaborn CP,Shively CA,Krukonis ES

更新日期：2015-11-16 00:00:00

abstract：UNLABELLED:The GlnPQ transporter from Lactococcus lactis has the remarkable feature of having two substrate-binding domains (SBDs) fused to the N terminus of the transmembrane domain (TMD), and thus four SBDs are present in the homodimeric complex. Although X-ray structures and ligand binding data are available for bot...

journal_title：Journal of bacteriology

authors： Fulyani F,Schuurman-Wolters GK,Slotboom DJ,Poolman B

更新日期：2015-11-09 00:00:00

abstract：UNLABELLED:Deacetylation of 7-aminocephalosporanic acid (7-ACA) at position C-3 provides valuable starting material for producing semisynthetic β-lactam antibiotics. However, few enzymes have been characterized in this process before now. Comparative analysis of the genome of the thermophilic bacterium Alicyclobacillus...

journal_title：Journal of bacteriology

authors： Ding JM,Yu TT,Han NY,Yu JL,Li JJ,Yang YJ,Tang XH,Xu B,Zhou JP,Tang HZ,Huang ZX

更新日期：2015-11-02 00:00:00

abstract：UNLABELLED:Bacteriophage λ N protein binds boxB RNA hairpins in the nut (N utilization) sites of immediate early λ transcripts and interacts with host factors to suppress transcriptional termination at downstream terminators. In opposition to λ N, the Nun protein of HK022 binds the boxBs of coinfecting λ transcripts, i...

journal_title：Journal of bacteriology

authors： Tawk CS,Ghattas IR,Smith CA

更新日期：2015-11-01 00:00:00

abstract：UNLABELLED:Cell shape has been suggested to play an important role in the regulation of bacterial attachment to surfaces and the formation of communities associated with surfaces. We found that a cardiolipin synthase (Δcls) mutant of the rod-shaped bacterium Rhodobacter sphaeroides--in which synthesis of the anionic, h...

journal_title：Journal of bacteriology

authors： Lin TY,Santos TM,Kontur WS,Donohue TJ,Weibel DB

更新日期：2015-11-01 00:00:00

abstract：UNLABELLED:Silica is deposited in and around the spore coat layer of Bacillus cereus, and enhances the spore's acid resistance. Several peptides and proteins, including diatom silaffin and silacidin peptides, are involved in eukaryotic silica biomineralization (biosilicification). Homologous sequence search revealed a ...

journal_title：Journal of bacteriology

authors： Motomura K,Ikeda T,Matsuyama S,Abdelhamid MA,Tanaka T,Ishida T,Hirota R,Kuroda A

更新日期：2015-10-26 00:00:00

abstract：UNLABELLED:An ability to sense and respond to changes in extracellular phosphate is critical for the survival of most bacteria. For Caulobacter crescentus, which typically lives in phosphate-limited environments, this process is especially crucial. Like many bacteria, Caulobacter responds to phosphate limitation throug...

journal_title：Journal of bacteriology

authors： Lubin EA,Henry JT,Fiebig A,Crosson S,Laub MT

更新日期：2015-10-19 00:00:00

abstract：UNLABELLED:Current knowledge regarding the mechanism that governs flagellar motor rotation in response to environmental stimuli stems mainly from the study of monotrichous and peritrichous bacteria. Little is known about how two polar flagella, one at each cell pole of the so-called amphitrichous bacterium, are coordin...

journal_title：Journal of bacteriology

authors： Murat D,Hérisse M,Espinosa L,Bossa A,Alberto F,Wu LF

更新日期：2015-10-01 00:00:00

abstract：UNLABELLED:Clostridium perfringens type D strains are usually associated with diseases of livestock, and their virulence requires the production of epsilon toxin (ETX). We previously showed (J. Li, S. Sayeed, S. Robertson, J. Chen, and B. A. McClane, PLoS Pathog 7:e1002429, 2011, http://dx.doi.org/10.1371/journal.ppat....

journal_title：Journal of bacteriology

authors： Li J,Freedman JC,McClane BA

更新日期：2015-10-01 00:00:00